Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 20/20 | 0.70 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21440993 | 0.90 | CTSC (0.69) | CTSCCTSK | |
| SCHEMBL18373190 | 0.90 | CTSC (0.70) | CTSCCTSK | |
| SCHEMBL18373199 | 0.86 | CTSC (0.70) | CTSCCTSK | |
| SCHEMBL18373189 | 0.85 | CTSC (0.63) | CTSCCTSK | |
| SCHEMBL21172943 | 0.84 | CTSC (0.70) | CTSCCTSK | |
| SCHEMBL18373207 | 0.83 | CTSC (0.71) | CTSCCTSK | |
| SCHEMBL21076200 | 0.83 | CTSC (0.64) | CTSCCTSK | |
| SCHEMBL18373186 | 0.82 | CTSC (0.68) | CTSCCTSK | |
| SCHEMBL18373182 | 0.82 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL18373161 | 0.82 | CTSC (1.00) | CTSCCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3511331-A1 | SPIROCYCLIC INHIBITORS OF CATHEPSIN C | Boehringer Ingelheim International GmbH (DE) | 2019-07-17 | — | — | EP | disclosed |