Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | MMP8 | P22894 | 3/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16147390 | 0.91 | SMN1; SMN2 (0.50) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL16148105 | 0.88 | PIM1 (0.47) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL16148299 | 0.84 | KMT2A (0.43) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL16147923 | 0.84 | NPC1 (0.46) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL16147236 | 0.83 | PIM1 (0.42) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL16148357 | 0.83 | PIM1 (0.42) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL16147347 | 0.82 | PIM1 (0.44) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL16147266 | 0.80 | KMT2A (0.45) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL16147482 | 0.80 | PIM1 (0.43) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL16148268 | 0.79 | PIM1 (0.42) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3514147-A1 | STEROIDAL COMPOUNDS WITH POTENT ANDROGEN RECEPTOR DOWN-REGULATION AND ANTI PROSTATE CANCER ACTIVITY | University of Maryland, Baltimore (US) | 2019-07-24 | — | — | EP | disclosed |