Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 17/20 | 0.44 |
| ▸ | CNR2 | P34972 | 13/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1753267 | 0.92 | CNR1 (0.44) | CNR1CNR2KMT2AOPRL1KCNH2 | |
| SCHEMBL1753272 | 0.91 | CNR1 (0.41) | CNR1CNR2KMT2AOPRL1KCNH2 | |
| SCHEMBL1753184 | 0.91 | KDM4E (0.43) | CNR1CNR2KMT2AOPRL1KCNH2 | |
| SCHEMBL1689160 | 0.91 | CNR1 (0.43) | CNR1CNR2KMT2AOPRL1KCNH2 | |
| SCHEMBL1753254 | 0.89 | CNR1 (0.43) | CNR1CNR2KMT2AOPRL1KCNH2 | |
| SCHEMBL1753450 | 0.88 | CNR1 (0.45) | CNR1CNR2KMT2AOPRL1 | |
| SCHEMBL1689275 | 0.87 | CNR1 (0.40) | CNR1CNR2KMT2AOPRL1KCNH2 | |
| SCHEMBL1753304 | 0.87 | CNR1 (0.45) | CNR1CNR2KMT2AOPRL1KCNH2 | |
| SCHEMBL1753616 | 0.87 | CNR1 (0.42) | CNR1CNR2OPRL1KCNH2 | |
| SCHEMBL1689142 | 0.87 | GRM1 (0.42) | CNR1CNR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158634-B2 | Compounds and compositions as inhibitors of cannabinoid receptor 1 activity | IRM LLC (BM) | 2012-04-17 | — | — | US | disclosed |