Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | PRF1 | P14222 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118766 | 0.90 | MAPT (0.45) | FFAR4MAPTLMNAGAAMAPK1 | |
| SCHEMBL2120005 | 0.86 | FFAR4 (0.48) | FFAR4CYP19A1MAPTSYKALDH1A1 | |
| SCHEMBL2118403 | 0.86 | FFAR4 (0.54) | FFAR4GABRG2GABRB3GABRA3PKM | |
| SCHEMBL2117837 | 0.81 | STAT3 (0.60) | FFAR4GABRG2GABRB3GABRA3PKM | |
| SCHEMBL2119745 | 0.79 | FFAR4 (0.64) | FFAR4GABRG2GABRB3GABRA3PKM | |
| SCHEMBL2117670 | 0.79 | MAPT (0.53) | FFAR4GABRG2GABRB3GABRA3PKM | |
| SCHEMBL2119453 | 0.78 | MEN1 (0.59) | FFAR4GABRG2GABRB3GABRA3PKM | |
| SCHEMBL2120416 | 0.78 | FFAR4 (0.53) | FFAR4GABRG2GABRB3GABRA3PKM | |
| SCHEMBL2120365 | 0.78 | SYK (0.57) | FFAR4GABRG2GABRB3GABRA3PKM | |
| SCHEMBL2117686 | 0.77 | FFAR4 (0.61) | FFAR4GABRG2GABRB3GABRA3PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | ELARA PHARMACEUTICALS GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | HIF1AN, HIF1A, EGLN2 | FFAR4 4059/4885GABRG2 4604/4885GABRB3 4684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.