Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tetrylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrylammonium SCHEMBL27806951 | 0.91 | KCNH2 (0.47) | KCNH2LMNACYP2D6CYP2C9TSHR | |
| Sulfuric Acid SCHEMBL16294962 | 0.90 | KCNH2 (0.57) | KCNH2CA2MEN1KMT2ACETP | |
| Sulfuric Acid SCHEMBL2347222 | 0.90 | KCNH2 (0.57) | KCNH2CA2MEN1KMT2ACETP | |
| Sulfuric Acid SCHEMBL10969631 | 0.90 | KCNH2 (0.57) | KCNH2CA2MEN1KMT2ACETP | |
| Sulfuric Acid SCHEMBL16294961 | 0.90 | KCNH2 (0.57) | KCNH2CA2MEN1KMT2ACETP | |
| Sulfuric Acid SCHEMBL2346281 | 0.90 | KCNH2 (0.57) | KCNH2CA2MEN1KMT2ACETP | |
| Sulfuric Acid SCHEMBL2346286 | 0.90 | KCNH2 (0.57) | KCNH2CA2MEN1KMT2ACETP | |
| Sulfuric Acid SCHEMBL15752866 | 0.90 | KCNH2 (0.57) | KCNH2CA2MEN1KMT2ACETP | |
| Sulfuric Acid SCHEMBL544764 | 0.90 | KCNH2 (0.57) | KCNH2CA2MEN1KMT2ACETP | |
| Sulfuric Acid SCHEMBL64908 | 0.90 | KCNH2 (0.57) | KCNH2CA2MEN1KMT2ACETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8697788-B2 | Polycarbonate resin composition and molded article thereof | TEIJIN CHEMICALS, LTD. (JP) | 2014-04-15 | — | — | US | disclosed |
| US-20120095141-A1 | POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | TEIJIN CHEMICALS, LTD. (JP) | 2012-04-19 | — | — | US | disclosed |
| US-7148313-B2 | Polycarbonate resin composition and molded articles thereof | TEIJIN CHEMICALS, LTD. (JP) | 2006-12-12 | — | — | US | disclosed |
| US-20050215750-A1 | Polycarbonate resin composition and molded articles thereof | TEIJIN CHEMICALS, LTD. (JP) | 2005-09-29 | — | — | US | disclosed |