Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 19/20 | 0.60 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21179429 | 0.89 | KLKB1 (0.60) | KLKB1MAP4K1CACNA1GCACNA1HCACNA1I | |
| SCHEMBL21177369 | 0.89 | KLKB1 (0.76) | KLKB1MAP4K1 | |
| SCHEMBL19780091 | 0.88 | KLKB1 (0.77) | KLKB1MAP4K1CACNA1GCACNA1HCACNA1I | |
| SCHEMBL21185846 | 0.83 | KLKB1 (0.80) | KLKB1MAP4K1CACNA1GCACNA1HCACNA1I | |
| SCHEMBL21177966 | 0.80 | KLKB1 (0.71) | KLKB1 | |
| SCHEMBL21185838 | 0.79 | KLKB1 (0.47) | KLKB1CACNA1GCACNA1HCACNA1I | |
| SCHEMBL24117387 | 0.78 | KLKB1 (0.74) | KLKB1MAP4K1 | |
| SCHEMBL21190227 | 0.78 | KLKB1 (0.59) | KLKB1MAP4K1 | |
| SCHEMBL21182292 | 0.77 | KLKB1 (0.55) | KLKB1MAP4K1 | |
| SCHEMBL21178101 | 0.77 | KLKB1 (0.77) | KLKB1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019142053-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-07-25 | — | — | WO | disclosed |