Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MET | P08581 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SCD | O00767 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21186031 | 0.93 | NPC1 (0.54) | MAPTPOLBKDM4ELMNAHPGD | |
| SCHEMBL21186169 | 0.92 | CSNK1D (0.49) | MAPTPOLBKDM4ELMNAHPGD | |
| SCHEMBL21186049 | 0.90 | POLB (0.56) | MAPTPOLBKDM4ELMNAHPGD | |
| SCHEMBL21186123 | 0.89 | MAPT (0.52) | MAPTPOLBKDM4ELMNAHPGD | |
| SCHEMBL21186233 | 0.85 | NPC1 (0.47) | MAPTPOLBHTTMETNPC1 | |
| SCHEMBL21186156 | 0.85 | MAPT (0.59) | MAPTPOLBKDM4ELMNAHPGD | |
| SCHEMBL21177804 | 0.83 | MAPT (0.66) | MAPTPOLBKDM4ELMNAHPGD | |
| SCHEMBL21186251 | 0.82 | NPC1 (0.57) | MAPTPOLBKDM4ELMNAHPGD | |
| SCHEMBL21186158 | 0.82 | SCD (0.51) | MAPTPOLBKDM4ELMNAHPGD | |
| SCHEMBL21186132 | 0.82 | DCLK1 (0.51) | MAPTPOLBKDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |