SCHEMBL21178372

SCHEMBL21178372

Clc1nc(-c2ccc3ccccc3c2)nc(-c2ccc3oc4ccccc4c3c2)n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.45
KDM4E B2RXH2 5/20 0.41
ALDH1A1 P00352 5/20 0.41
NPC1 O15118 4/20 0.41
MAPT P10636 4/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
RAB9A P51151 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
HPGD P15428 3/20 0.41
CHEK2 O96017 1/20 0.40
CYP1A2 P05177 4/20 0.39
CYP2C9 P11712 2/20 0.39
CASP3 P42574 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
CYP2C19 P33261 1/20 0.39
HSD17B10 Q99714 3/20 0.37
TP53 P04637 1/20 0.37
TSHR P16473 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25818509 0.95 AHR (0.41) AHRKDM4EALDH1A1NPC1MAPT
SCHEMBL25818546 0.94 AHR (0.40) AHRKDM4EALDH1A1NPC1MAPT
SCHEMBL23079609 0.93 AHR (0.51) AHRKDM4EALDH1A1NPC1MAPT
SCHEMBL23384902 0.93 MAPT (0.47) AHRKDM4EALDH1A1NPC1MAPT
SCHEMBL23920329 0.93 MAPT (0.47) AHRKDM4EALDH1A1NPC1MAPT
SCHEMBL23283905 0.92 AHR (0.46) AHRKDM4EALDH1A1NPC1MAPT
SCHEMBL30512300 0.91 AHR (0.49) AHRKDM4EALDH1A1NPC1MAPT
SCHEMBL20894572 0.91 AHR (0.49) AHRKDM4EALDH1A1NPC1MAPT
SCHEMBL23283871 0.91 AHR (0.38) AHRKDM4EALDH1A1NPC1MAPT
SCHEMBL30997077 0.90 AHR (0.51) AHRKDM4EALDH1A1NPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021182834-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-09-16 WO disclosed
WO-2019143109-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 주식회사 두산 2019-07-25 WO disclosed
WO-2019143109-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 주식회사 두산 2019-07-25 WO disclosed