Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 18/20 | 0.75 |
| ▸ | BCL2 | P10415 | 17/20 | 0.75 |
| ▸ | BAD | Q92934 | 4/20 | 0.75 |
| ▸ | BCL2L2 | Q92843 | 3/20 | 0.75 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.75 |
| ▸ | ASPH | Q12797 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21179134 | 1.00 | BCL2L1 (0.75) | BCL2L1BCL2BADBCL2L2BCL2L11 | |
| SCHEMBL31283521 | 1.00 | BCL2L1 (0.75) | BCL2L1BCL2BADBCL2L2BCL2L11 | |
| SCHEMBL21179193 | 0.94 | BCL2L1 (0.74) | BCL2L1BCL2BADBCL2L2BCL2L11 | |
| SCHEMBL21179191 | 0.94 | BCL2L1 (0.74) | BCL2L1BCL2BADBCL2L2BCL2L11 | |
| SCHEMBL21179293 | 0.93 | BCL2L1 (0.75) | BCL2L1BCL2BADBCL2L2BCL2L11 | |
| SCHEMBL21179292 | 0.93 | BCL2L1 (0.75) | BCL2L1BCL2BADBCL2L2BCL2L11 | |
| SCHEMBL21179258 | 0.93 | BCL2L1 (0.79) | BCL2L1BCL2BADBCL2L2BCL2L11 | |
| SCHEMBL21179253 | 0.93 | BCL2L1 (0.79) | BCL2L1BCL2BADBCL2L2BCL2L11 | |
| SCHEMBL31282960 | 0.93 | BCL2L1 (0.79) | BCL2L1BCL2BADBCL2L2BCL2L11 | |
| SCHEMBL19014626 | 0.92 | BCL2L1 (0.82) | BCL2L1BCL2BADBCL2L2BCL2L11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3743069-B1 | BCL-2 PROTEINS DEGRADERS FOR CANCER TREATMENT | BIOVENTURES LLC (US) | 2025-08-06 | — | — | EP | disclosed |
| EP-3743069-A1 | BCL-2 PROTEINS DEGRADERS FOR CANCER TREATMENT | BioVentures, LLC (US) | 2020-12-02 | — | — | EP | disclosed |
| WO-2019144117-A1 | BCL-2 PROTEINS DEGRADERS FOR CANCER TREATMENT | BIOVENTURES, LLC (US) | 2019-07-25 | — | — | WO | disclosed |