Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.48 |
| ▸ | PIK3R2 | O00459 | 11/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21174690 | 0.87 | PIK3CD (0.54) | PIK3CDPIK3CGPIK3R1PIK3R2PIK3CA | |
| SCHEMBL18056720 | 0.87 | PIK3CD (0.53) | PIK3CDPIK3CGPIK3R2 | |
| SCHEMBL28968355 | 0.81 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3R2 | |
| SCHEMBL30418978 | 0.81 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3R2 | |
| SCHEMBL21174812 | 0.80 | PIK3CD (0.53) | PIK3CDPIK3CGPIK3R1PIK3R2PIK3CA | |
| SCHEMBL21174810 | 0.80 | PIK3CD (0.53) | PIK3CDPIK3CGPIK3R1PIK3R2PIK3CA | |
| SCHEMBL28968385 | 0.80 | PIK3CD (0.60) | PIK3CDPIK3CGPIK3R2 | |
| SCHEMBL30418541 | 0.80 | PIK3CD (0.60) | PIK3CDPIK3CGPIK3R2 | |
| SCHEMBL16663361 | 0.79 | PIK3CD (0.45) | PIK3CDPIK3CGPIK3R1PIK3CA | |
| SCHEMBL28968392 | 0.79 | PIK3CD (0.44) | PIK3CDPIK3CGPIK3R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3740468-A1 | SUBSTITUTED AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE | Sunshine Lake Pharma Co., Ltd. (CN) | 2020-11-25 | — | — | EP | disclosed |
| WO-2019143874-A1 | SUBSTITUTED AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2019-07-25 | — | — | WO | disclosed |