Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21180545 | 1.00 | KDM4E (0.40) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL21180700 | 0.93 | KDM4E (0.40) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL21180578 | 0.93 | KDM4E (0.40) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL16472820 | 0.87 | KDM4E (0.40) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL14725730 | 0.87 | KDM4E (0.40) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL15912228 | 0.86 | KDM4E (0.39) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL16472793 | 0.86 | KDM4E (0.39) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL16472805 | 0.86 | KDM4E (0.39) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL16472817 | 0.86 | KDM4E (0.39) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL16472807 | 0.86 | KDM4E (0.39) | KDM4EATML3MBTL1SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10361380-B2 | Heterocyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-07-23 | — | — | US | disclosed |