Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14725779 | 0.89 | CYP11B1 (0.48) | CYP11B1CYP3A4PDK2MAOAMAOB | |
| SCHEMBL15461872 | 0.86 | CYP11B1 (0.47) | CYP11B1CYP3A4PDK2GPR84HIPK2 | |
| SCHEMBL14725726 | 0.84 | CYP11B1 (0.54) | CYP11B1CYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL14725619 | 0.84 | MAPT (0.37) | KDM4EMAPTRAB9AMEN1KMT2A | |
| SCHEMBL14725773 | 0.84 | PDK2 (0.42) | CYP11B1CYP1A2CYP3A4ALDH1A1PDK2 | |
| SCHEMBL15460244 | 0.82 | PDK2 (0.40) | CYP11B1CYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL16472813 | 0.82 | CYP11B1 (0.54) | CYP11B1CYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL15461894 | 0.81 | MAPT (0.36) | CYP1A2KDM4EMAPTRAB9AMEN1 | |
| SCHEMBL15460196 | 0.80 | PDK2 (0.42) | CYP11B1CYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL22243864 | 0.79 | PDK2 (0.45) | CYP11B1CYP1A2CYP3A4GAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10361380-B2 | Heterocyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-07-23 | — | — | US | disclosed |