Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15946239 | 0.84 | KDM4E (0.39) | MAPTKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL15912276 | 0.83 | BTK (0.37) | BTKPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL15946259 | 0.82 | CYP11B1 (0.38) | BTKPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL21180594 | 0.82 | BTK (0.35) | BTKPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL21180638 | 0.81 | MAPT (0.34) | MAPTKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL15946243 | 0.80 | KDM4E (0.39) | MAPTKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL15946248 | 0.80 | CYP11B1 (0.46) | PIK3CAPGRCYP19A1MAPTKDM4E | |
| SCHEMBL15912275 | 0.79 | BTK (0.35) | BTKPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL16472779 | 0.78 | CYP11B1 (0.41) | MAPTKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL16472821 | 0.78 | CYP11B1 (0.41) | MAPTKDM4ERAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10361380-B2 | Heterocyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-07-23 | — | — | US | disclosed |