Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.81 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.81 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.81 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.81 |
| ▸ | KDR | P35968 | 4/20 | 0.81 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.81 |
| ▸ | FLT1 | P17948 | 2/20 | 0.81 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.81 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.81 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.81 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.81 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.81 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.81 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.81 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.81 |
| ▸ | TLK2 | Q86UE8 | 6/20 | 0.76 |
| ▸ | PDPK1 | O15530 | 4/20 | 0.67 |
| ▸ | AKT2 | P31751 | 1/20 | 0.64 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.64 |
| ▸ | JAK3 | P52333 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21183 | 1.00 | HDAC3 (0.81) | HDAC3HDAC1HDAC2PDGFRBKDR | |
| SCHEMBL26087 | 0.99 | HDAC3 (0.81) | HDAC3HDAC1HDAC2PDGFRBKDR | |
| SCHEMBL12473993 | 0.90 | PDGFRB (0.85) | HDAC3HDAC1HDAC2PDGFRBKDR | |
| SCHEMBL12473992 | 0.90 | PDGFRB (0.85) | HDAC3HDAC1HDAC2PDGFRBKDR | |
| SCHEMBL24642 | 0.90 | HDAC3 (1.00) | HDAC3HDAC1HDAC2PDGFRBKDR | |
| SCHEMBL29924 | 0.90 | HDAC3 (1.00) | HDAC3HDAC1HDAC2PDGFRBKDR | |
| SCHEMBL21116 | 0.89 | HDAC3 (1.00) | HDAC3HDAC1HDAC2PDGFRBKDR | |
| SCHEMBL22682 | 0.89 | PDGFRB (0.85) | HDAC3HDAC1HDAC2PDGFRBKDR | |
| SCHEMBL22683 | 0.89 | PDGFRB (0.85) | HDAC3HDAC1HDAC2PDGFRBKDR | |
| SCHEMBL21115 | 0.89 | HDAC3 (1.00) | HDAC3HDAC1HDAC2PDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025726-A1 | Novel Hybrid Compounds | UNIVERSITY OF GREENWICH (GB) | 2012-03-01 | — | — | WO | disclosed |