Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | SCD | O00767 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ACP1 | P24666 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21186205 | 0.86 | SCD (0.64) | SMN1; SMN2NPC1RAB9ASCDKDM4E | |
| SCHEMBL21186112 | 0.85 | SCD (0.56) | SMN1; SMN2NPC1RAB9ASCDKDM4E | |
| SCHEMBL21186014 | 0.83 | SCD (0.61) | SMN1; SMN2NPC1RAB9ASCDMAPT | |
| SCHEMBL21186010 | 0.82 | MAPT (0.52) | SMN1; SMN2NPC1RAB9ASCDKDM4E | |
| SCHEMBL21179394 | 0.82 | NPC1 (0.53) | SMN1; SMN2NPC1RAB9ASCDKDM4E | |
| SCHEMBL21186275 | 0.79 | PIK3CG (0.62) | SMN1; SMN2NPC1RAB9ASCDMAPT | |
| SCHEMBL21186001 | 0.79 | MAPT (0.67) | SMN1; SMN2NPC1RAB9ASCDKDM4E | |
| SCHEMBL21186009 | 0.77 | SCD (0.55) | SMN1; SMN2NPC1RAB9ASCDMAPT | |
| SCHEMBL21186111 | 0.77 | MAPT (0.53) | SMN1; SMN2NPC1RAB9AKDM4EMAPT | |
| SCHEMBL23607120 | 0.77 | TOP1 (0.61) | SMN1; SMN2NPC1RAB9ASCDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |