Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 4/20 | 0.35 |
| ▸ | SRC | P12931 | 2/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | KIF5B | P33176 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 3/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | FLT1 | P17948 | 2/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | TEK | Q02763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21187495 | 0.93 | EGFR (0.37) | EGFRHSP90AA1HSP90AB1DRD1CRHR1 | |
| SCHEMBL21187575 | 0.87 | EGFR (0.36) | EGFRERBB2CLK1 | |
| SCHEMBL21187497 | 0.84 | EGFR (0.36) | EGFRKDRRETKIF5BFLT4 | |
| SCHEMBL22598821 | 0.84 | EGFR (0.39) | EGFRDRD1CRHR1 | |
| SCHEMBL21187440 | 0.81 | SLC34A1 (0.35) | EGFRERBB2CLK1 | |
| SCHEMBL22599078 | 0.78 | HSP90AA1 (0.37) | EGFRHSP90AA1HSP90AB1SRCCTSD | |
| SCHEMBL24158349 | 0.78 | HSP90AA1 (0.37) | EGFRHSP90AA1HSP90AB1DRD1CRHR1 | |
| SCHEMBL21187493 | 0.77 | DHODH (0.39) | EGFRERBB2 | |
| SCHEMBL15688522 | 0.76 | DRD1 (0.53) | HSP90AA1HSP90AB1DRD1CRHR1 | |
| SCHEMBL21187437 | 0.75 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1DRD1CRHR1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3740474-B1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2022-01-05 | — | — | EP | disclosed |
| US-20200339543-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2020-10-29 | — | — | US | disclosed |
| WO-2019141972-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339543-A1 | AGRICULTURAL CHEMICALS | ABAT, BRDT, GABBR1 | EGFR 4547/4885HSP90AA1 3401/4885HSP90AB1 2762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.