SCHEMBL21188134

SCHEMBL21188134

c1ccc(-c2ccc(-c3nc(-c4ccc(-c5ccccc5)cc4)nc(-c4ccc5ccc(-c6ccc(-c7nc(-c8ccccc8)nc(-c8ccccc8)n7)cc6)cc5c4)n3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.59
ESR2 Q92731 5/20 0.59
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
ALDH1A1 P00352 3/20 0.52
MAPT P10636 2/20 0.52
HPGD P15428 2/20 0.52
KDM4E B2RXH2 2/20 0.50
TP53 P04637 1/20 0.50
CYP1A2 P05177 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HSD17B10 Q99714 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
BACE1 P56817 1/20 0.48
NTSR1 P30989 1/20 0.47
CYP17A1 P05093 1/20 0.46
CYP19A1 P11511 1/20 0.46
CYP11B1 P15538 1/20 0.46
CYP11B2 P19099 1/20 0.46
ADORA2A P29274 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21188130 1.00 ESR1 (0.59) ESR1ESR2MEN1KMT2AALDH1A1
SCHEMBL23633611 1.00 ESR1 (0.59) ESR1ESR2MEN1KMT2AALDH1A1
SCHEMBL21188129 1.00 ESR1 (0.59) ESR1ESR2MEN1KMT2AALDH1A1
SCHEMBL23633506 1.00 ESR1 (0.59) ESR1ESR2MEN1KMT2AALDH1A1
SCHEMBL26154474 0.98 ESR1 (0.57) ESR1ESR2MEN1KMT2AALDH1A1
SCHEMBL16785867 0.98 ESR1 (0.55) ESR1ESR2MEN1KMT2AALDH1A1
SCHEMBL15850715 0.98 ESR1 (0.61) ESR1ESR2MEN1KMT2AALDH1A1
SCHEMBL17655916 0.98 ESR1 (0.61) ESR1ESR2MEN1KMT2AALDH1A1
SCHEMBL21446906 0.96 MEN1 (0.56) ESR1ESR2MEN1KMT2AALDH1A1
SCHEMBL23633641 0.96 MEN1 (0.56) ESR1ESR2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210050528-A1 ORGANIC LIGHT EMITTING DIODE LG CHEM, LTD. (KR) 2021-02-18 US disclosed
WO-2019143151-A1 ORGANIC LIGHT-EMITTING DIODE 주식회사 엘지화학 2019-07-25 WO disclosed