Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 5/20 | 0.34 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.33 |
| ▸ | FUCA1 | P04066 | 4/20 | 0.31 |
| ▸ | GLA | P06280 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GLB1 | P16278 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18663800 | 1.00 | GBA1 (0.34) | GBA1MAN1B1FUCA1GLAGAA | |
| SCHEMBL19079551 | 1.00 | GBA1 (0.34) | GBA1MAN1B1FUCA1GLAGAA | |
| SCHEMBL19079554 | 1.00 | GBA1 (0.34) | GBA1MAN1B1FUCA1GLAGAA | |
| SCHEMBL19079553 | 1.00 | GBA1 (0.34) | GBA1MAN1B1FUCA1GLAGAA | |
| SCHEMBL18663513 | 1.00 | GBA1 (0.34) | GBA1MAN1B1FUCA1GLAGAA | |
| SCHEMBL23583924 | 1.00 | GBA1 (0.34) | GBA1MAN1B1FUCA1GLAGAA | |
| SCHEMBL19079552 | 1.00 | GBA1 (0.34) | GBA1MAN1B1FUCA1GLAGAA | |
| SCHEMBL21385654 | 0.84 | GBA1 (0.42) | GBA1MAN1B1 | |
| SCHEMBL12778997 | 0.84 | GBA1 (0.42) | GBA1MAN1B1 | |
| SCHEMBL18663731 | 0.84 | GBA1 (0.42) | GBA1MAN1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019143719-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS, INC. (US) | 2019-07-25 | — | — | WO | disclosed |