Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.64 |
| ▸ | CA2 | P00918 | 3/20 | 0.64 |
| ▸ | ACR | P10323 | 3/20 | 0.63 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.63 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | STS | P08842 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12895907 | 0.94 | CA1 (0.75) | CA1CA2ACRHGFACPRSS1 | |
| SCHEMBL16751100 | 0.94 | CA1 (0.75) | CA1CA2ACRHGFACPRSS1 | |
| SCHEMBL16573857 | 0.94 | CA1 (0.75) | CA1CA2ACRHGFACPRSS1 | |
| SCHEMBL7518320 | 0.94 | CA1 (0.72) | CA1CA2ACRHGFACPRSS1 | |
| SCHEMBL12023304 | 0.93 | TDP1 (0.69) | CA1CA2ACRHGFACPRSS1 | |
| SCHEMBL14346594 | 0.93 | TDP1 (0.69) | CA1CA2ACRHGFACPRSS1 | |
| SCHEMBL16425786 | 0.93 | TDP1 (0.69) | CA1CA2ACRHGFACPRSS1 | |
| SCHEMBL15382238 | 0.93 | TSHR (0.66) | CA1CA2ACRHGFACPRSS1 | |
| SCHEMBL14346590 | 0.93 | TDP1 (0.69) | CA1CA2ACRHGFACPRSS1 | |
| SCHEMBL16425787 | 0.93 | TDP1 (0.69) | CA1CA2ACRHGFACPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020078938-A1 | DIELECTRIC COPOLYMER MATERIALS | MERCK PATENT GMBH (DE) | 2020-04-23 | — | — | WO | disclosed |
| WO-2019141833-A1 | DIELECTRIC MATERIALS | MERCK PATENT GMBH (DE) | 2019-07-25 | — | — | WO | disclosed |