Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 3/20 | 0.51 |
| ▸ | BCL6 | P41182 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14502832 | 0.84 | IGF1R (0.53) | IGF1RBCL6EGFRMAPTGAA | |
| SCHEMBL3942497 | 0.81 | IGF1R (0.50) | IGF1REGFRKDM4EALDH1A1HTT | |
| SCHEMBL15068000 | 0.79 | BRD4 (0.48) | IGF1REGFRMAPTGAATDP1 | |
| SCHEMBL10138755 | 0.77 | IGF1R (0.46) | IGF1RBCL6EGFRMAPTGAA | |
| SCHEMBL15999439 | 0.74 | MEN1 (0.56) | IGF1REGFRMAPTGAATDP1 | |
| SCHEMBL29941236 | 0.73 | IGF1R (0.57) | IGF1REGFRTDP1MEN1LMNA | |
| SCHEMBL14027292 | 0.73 | IGF1R (0.57) | IGF1REGFRTDP1MEN1LMNA | |
| SCHEMBL4414071 | 0.72 | MAPT (0.43) | IGF1RMAPTGAAKDM4EMEN1 | |
| SCHEMBL2279335 | 0.72 | DHODH (0.56) | IGF1REGFRMAPTGAATDP1 | |
| SCHEMBL2492555 | 0.71 | CDK2 (0.55) | IGF1RBCL6MAPTGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141131-A1 | BROMODOMAIN INHIBITOR COMPOUND AND USE THEREOF | 中国科学院上海药物研究所 | 2019-07-25 | — | — | WO | disclosed |
| US-9359548-B2 | Organic electroluminescent device | UDC IRELAND LIMITED (IE) | 2016-06-07 | — | — | US | disclosed |