SCHEMBL2120140

SCHEMBL2120140

CCCCCCOc1ccc([C]=O)cc1

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.61
TP53 P04637 1/20 0.59
TSHR P16473 1/20 0.59
PLA2G4B P0C869 5/20 0.57
LTA4H P09960 3/20 0.55
RARB P10826 3/20 0.54
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
PLA2G4A P47712 1/20 0.51
KDM4E B2RXH2 1/20 0.51
ALDH1A1 P00352 1/20 0.51
HPGD P15428 1/20 0.51
HTT P42858 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2121574 1.00 NR5A1 (0.61) NR5A1TP53TSHRPLA2G4BLTA4H
SCHEMBL1957829 1.00 NR5A1 (0.61) NR5A1TP53TSHRPLA2G4BLTA4H
SCHEMBL1960170 1.00 NR5A1 (0.61) NR5A1TP53TSHRPLA2G4BLTA4H
SCHEMBL3458574 1.00 NR5A1 (0.61) NR5A1TP53TSHRPLA2G4BLTA4H
SCHEMBL1958536 1.00 NR5A1 (0.61) NR5A1TP53TSHRPLA2G4BLTA4H
SCHEMBL2119769 1.00 NR5A1 (0.61) NR5A1TP53TSHRPLA2G4BLTA4H
SCHEMBL2119770 1.00 NR5A1 (0.61) NR5A1TP53TSHRPLA2G4BLTA4H
SCHEMBL54703 1.00 NR5A1 (0.61) NR5A1TP53TSHRPLA2G4BLTA4H
SCHEMBL1960613 1.00 NR5A1 (0.61) NR5A1TP53TSHRPLA2G4BLTA4H
SCHEMBL2120179 0.98 NR5A1 (0.58) NR5A1TP53TSHRPLA2G4BLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4297277-A FUNGICIDES ANTISEPTICS ELI LILLY AND COMPANY (US) 1981-10-27 US claimed
US-4293486-A ANTIFUNGAL PEPTIDES ELI LILLY AND COMPANY (US) 1981-10-06 US claimed
US-4293484-A ANTIFUNGAL PEPTIDES ELI LILLY AND COMPANY (US) 1981-10-06 US claimed
US-4293489-A ANTIFUNGAL PEPTIDES ELI LILLY AND COMPANY (US) 1981-10-06 US claimed
US-4289692-A CYCLIC PEPTIDE ANTIBIOTICS ELI LILLY AND COMPANY (US) 1981-09-15 US claimed
EP-0031220-A1 Derivatives of cyclic peptide nuclei ELI LILLY AND COMPANY (US) 1981-07-01 EP claimed
CN-101522657-B STAT3/5 activation inhibitor OTSUKA PHARMACEUTICAL CO.,LTD. (JP) 2014-10-15 CN disclosed
US-20140178606-A1 CELLULOSE ACYLATE FILM, POLARIZER, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2014-06-26 US disclosed
EP-1957073-B1 MEDICINAL DRUG OTSUKA PHARMA CO LTD (JP) 2014-04-23 EP disclosed
EP-2612858-A1 STAT3/5 activation inhibitor OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-07-10 EP disclosed
US-8477275-B2 Optical film and liquid crystal display device FUJIFILM CORPORATION (JP) 2013-07-02 US disclosed
US-20130128359-A1 OPTICAL FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY APPARATUS FUJIFILM CORPORATION (JP) 2013-05-23 US disclosed
CN-1993339-B Aromatic compound OTSUKA PHARMA CO LTD 2013-05-22 CN disclosed
US-4308162-A Novel yellow azo dyes and dichroic liquid crystal compositions made therewith GENERAL ELECTRIC COMPANY (US) 1981-12-29 US disclosed
US-4308161-A FOR UPGRADING BLACK COLOR OF BLACK LIQUID CRYSTAL DISPLAYS GENERAL ELECTRIC COMPANY (US) 1981-12-29 US disclosed
US-4297277-A FUNGICIDES ANTISEPTICS ELI LILLY AND COMPANY (US) 1981-10-27 US disclosed
US-4293486-A ANTIFUNGAL PEPTIDES ELI LILLY AND COMPANY (US) 1981-10-06 US disclosed
US-4293484-A ANTIFUNGAL PEPTIDES ELI LILLY AND COMPANY (US) 1981-10-06 US disclosed
US-4289692-A CYCLIC PEPTIDE ANTIBIOTICS ELI LILLY AND COMPANY (US) 1981-09-15 US disclosed
EP-0031220-A1 Derivatives of cyclic peptide nuclei ELI LILLY AND COMPANY (US) 1981-07-01 EP disclosed