SCHEMBL21202687

SCHEMBL21202687

Nc1ncnc2c1ncn2C1OC2CO[P@@](=O)(S)OC3C(O)C(COP(=O)(O)OC2C1F)OC3n1cnc2c(N)ncnc21

nearest known ligand 0.90

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 20/20 0.90

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18937576 1.00 STING1 (0.90) STING1
SCHEMBL19239970 1.00 STING1 (0.90) STING1
SCHEMBL19239971 1.00 STING1 (0.90) STING1
SCHEMBL18927170 1.00 STING1 (0.90) STING1
SCHEMBL18937044 1.00 STING1 (0.90) STING1
SCHEMBL22292045 1.00 STING1 (0.90) STING1
SCHEMBL18937601 1.00 STING1 (0.90) STING1
SCHEMBL22905231 1.00 STING1 (0.90) STING1
SCHEMBL22292036 1.00 STING1 (0.90) STING1
SCHEMBL18937059 1.00 STING1 (0.90) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10364266-B2 Compounds GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2019-07-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10364266-B2 Compounds STING1, IRF3, TLR9 STING1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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