Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 1/20 | 0.68 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.68 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.48 |
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16385901 | 1.00 | CDK5 (0.68) | CDK5CDK5R1NR1I3GRIN1GRIN2B | |
| SCHEMBL21206146 | 1.00 | CDK5 (0.68) | CDK5CDK5R1NR1I3GRIN1GRIN2B | |
| SCHEMBL14883710 | 1.00 | CDK5 (0.68) | CDK5CDK5R1NR1I3GRIN1GRIN2B | |
| SCHEMBL5842843 | 0.83 | CDK5 (0.57) | CDK5CDK5R1NR1I3GRIN1GRIN2B | |
| SCHEMBL28142697 | 0.83 | CDK5 (0.57) | CDK5CDK5R1NR1I3GRIN1GRIN2B | |
| SCHEMBL5842846 | 0.83 | CDK5 (0.57) | CDK5CDK5R1NR1I3GRIN1GRIN2B | |
| SCHEMBL21206227 | 0.82 | CDK5 (0.68) | CDK5CDK5R1NR1I3GRIN1GRIN2B | |
| SCHEMBL21586229 | 0.82 | CDK5 (0.68) | CDK5CDK5R1NR1I3GRIN1GRIN2B | |
| SCHEMBL18845289 | 0.82 | CDK5 (0.68) | CDK5CDK5R1NR1I3GRIN1GRIN2B | |
| SCHEMBL17739680 | 0.82 | CDK5 (0.68) | CDK5CDK5R1NR1I3GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556055-B1 | SHIP INHIBITORS AND USES THEREOF | THE RESEARCH FOUNDATION OF THE STATE UNIV OF NEW YORK (US) | 2019-07-31 | — | — | EP | disclosed |