Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.74 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.58 |
| ▸ | MMP12 | P39900 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 6/20 | 0.51 |
| ▸ | DRD2 | P14416 | 5/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12844300 | 0.91 | PARP1 (0.78) | PARP1NR3C2MMP12DRD4DRD2 | |
| SCHEMBL31033201 | 0.91 | PARP1 (0.78) | PARP1NR3C2MMP12DRD4DRD2 | |
| SCHEMBL11004751 | 0.90 | PARP1 (0.70) | PARP1NR3C2MMP12DRD4DRD2 | |
| SCHEMBL11006154 | 0.90 | PARP1 (0.70) | PARP1NR3C2MMP12DRD4DRD2 | |
| SCHEMBL21177010 | 0.89 | PARP1 (0.79) | PARP1NR3C2MMP12DRD4DRD2 | |
| SCHEMBL11002313 | 0.88 | PARP1 (0.77) | PARP1NR3C2MMP12DRD4DRD2 | |
| SCHEMBL4178404 | 0.86 | PARP1 (0.65) | PARP1NR3C2MMP12DRD4DRD2 | |
| SCHEMBL9244955 | 0.86 | PARP1 (0.65) | PARP1NR3C2MMP12DRD4DRD2 | |
| SCHEMBL532134 | 0.85 | PARP1 (1.00) | PARP1NR3C2MMP12DRD4DRD2 | |
| SCHEMBL4257167 | 0.84 | PARP1 (0.70) | PARP1NR3C2MMP12DRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019145919-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | CADILA HEALTHCARE LIMITED (IN) | 2019-08-01 | — | — | WO | disclosed |