SCHEMBL21208412

SCHEMBL21208412

O=C1CC(O)(CC(=O)OC2CCCCCC2)C(=O)O1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.51
CYP19A1 P11511 2/20 0.38
NAAA Q02083 2/20 0.37
HTT P42858 1/20 0.36
ALDH1A1 P00352 9/20 0.35
KDM4E B2RXH2 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
GAA P10253 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
HPGD P15428 2/20 0.33
MAPK1 P28482 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19520032 1.00 CYP2C19 (0.51) CYP2C19CYP19A1NAAAHTTALDH1A1
SCHEMBL23862377 1.00 CYP2C19 (0.51) CYP2C19CYP19A1NAAAHTTALDH1A1
SCHEMBL22745719 0.99 CYP2C19 (0.49) CYP2C19CYP19A1NAAAHTTALDH1A1
SCHEMBL247910 0.70
SCHEMBL14422675 0.70 CYP2C19 (0.71) CYP2C19CYP19A1NAAAHTTALDH1A1
Water SCHEMBL8154773 0.70 AKR1B1 (0.33)
SCHEMBL2998541 0.70 CYP2C19 (0.71) CYP2C19CYP19A1NAAAHTTALDH1A1
SCHEMBL22478795 0.68 CYP2C19 (1.00) CYP2C19CYP19A1NAAAHTTALDH1A1
SCHEMBL22478840 0.66 CYP2C19 (0.96) CYP2C19CYP19A1NAAAHTTALDH1A1
SCHEMBL14236451 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210353665-A1 Polymer Hydrogels and Methods of Preparation Thereof GELESIS LLC (US) 2021-11-18 US disclosed
US-20200332025-A1 METHOD FOR PRODUCING HYDROGELS GELESIS LLC (US) 2020-10-22 US disclosed
US-20200046755-A1 POLYMER HYDROGELS AND METHODS OF PREPARATION THEREOF GELESIS LLC (US) 2020-02-13 US disclosed
US-10544233-B2 Method for producing hydrogels GELESIS LLC (US) 2020-01-28 US disclosed
US-20190233545-A1 METHOD FOR PRODUCING HYDROGELS COUPLING HIGH ELASTIC MODULUS AND ABSORBANCE GELESIS LLC (US) 2019-08-01 US disclosed