Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23424019 | 0.80 | HRH4 (0.43) | LMNAJAK3MEN1KMT2ATSHR | |
| SCHEMBL26788467 | 0.80 | HRH4 (0.44) | JAK3PDK2HRH4 | |
| SCHEMBL19563035 | 0.76 | PDK2 (0.40) | LMNASMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL16695435 | 0.75 | NOTUM (0.65) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL21285384 | 0.75 | HRH4 (0.49) | LMNAL3MBTL1SMN1; SMN2GAAALOX15 | |
| SCHEMBL15108582 | 0.73 | KDM4E (0.62) | LMNAL3MBTL1SMN1; SMN2GAAALOX15 | |
| SCHEMBL19314278 | 0.73 | USP2 (0.47) | LMNAL3MBTL1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL803661 | 0.73 | HRH4 (0.54) | HRH4 | |
| SCHEMBL6667369 | 0.72 | CHKA (0.50) | LMNASMN1; SMN2GAAMAPTJAK3 | |
| SCHEMBL21711135 | 0.72 | HRH4 (0.37) | GAAKDM4EHPGDHSD17B10HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3856735-B1 | FUSED BICYCLIC HETEROCYCLES AS THERAPEUTIC AGENTS | UNIV NEW YORK (US) | 2023-09-06 | — | — | EP | disclosed |
| WO-2019148005-A1 | INHIBITORS OF CBL-B AND METHODS OF USE THEREOF | NURIX THERAPEUTICS, INC. (US) | 2019-08-01 | — | — | WO | disclosed |