SCHEMBL21212381

SCHEMBL21212381

C[C@H](Cc1nncn1C)c1cccc(NC(=O)c2cc(C3CC3)nc(C3CC3)n2)c1

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29866944 1.00 CBLB (0.85) CBLB
SCHEMBL21212513 0.92 CBLB (1.00) CBLB
SCHEMBL29867637 0.92 CBLB (1.00) CBLB
SCHEMBL29866645 0.92 CBLB (1.00) CBLB
SCHEMBL21212174 0.92 CBLB (1.00) CBLB
SCHEMBL29536015 0.89 CBLB (0.79) CBLB
SCHEMBL21199814 0.88 CBLB (0.78) CBLB
SCHEMBL21199811 0.88 CBLB (0.78) CBLB
SCHEMBL29866923 0.88 CBLB (0.78) CBLB
SCHEMBL21212107 0.88 CBLB (1.00) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019148005-A1 INHIBITORS OF CBL-B AND METHODS OF USE THEREOF NURIX THERAPEUTICS, INC. (US) 2019-08-01 — — WO disclosed
Send feedback