SCHEMBL21212642

SCHEMBL21212642

Cn1cnnc1C(F)(F)C(F)c1cccc(N)c1

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 19/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29841764 0.87 CBLB (0.55) CBLB
SCHEMBL21200778 0.87 CBLB (0.55) CBLB
SCHEMBL29866426 0.74 CBLB (0.53) CBLB
SCHEMBL21200099 0.74 CBLB (0.53) CBLB
SCHEMBL21199967 0.74 CBLB (0.53) CBLB
SCHEMBL21200302 0.74 CBLB (0.53) CBLB
SCHEMBL29867362 0.74 CBLB (0.53) CBLB
SCHEMBL21200737 0.72 CBLB (0.54) CBLB
SCHEMBL21200404 0.72 CBLB (0.54) CBLB
SCHEMBL21200402 0.72 CBLB (0.54) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019148005-A1 INHIBITORS OF CBL-B AND METHODS OF USE THEREOF NURIX THERAPEUTICS, INC. (US) 2019-08-01 — — WO disclosed
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