SCHEMBL212158

SCHEMBL212158

CCCC(C)=NOS(=O)(=O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.51
ALDH1A1 P00352 5/20 0.44
KDM4E B2RXH2 3/20 0.44
KMT2A Q03164 2/20 0.44
POLB P06746 1/20 0.42
XBP1 P17861 4/20 0.41
MPI P34949 4/20 0.41
NPSR1 Q6W5P4 4/20 0.41
HSP90AA1 P07900 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
MAPK1 P28482 2/20 0.41
HSD11B1 P28845 1/20 0.40
PSIP1 O75475 1/20 0.40
S1PR2 O95136 3/20 0.39
LMNA P02545 3/20 0.39
RAB9A P51151 2/20 0.39
PKM P14618 2/20 0.39
HTT P42858 2/20 0.39
OPRM1 P35372 1/20 0.39
OPRD1 P41143 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL212157 1.00 MAPT (0.51) MAPTALDH1A1KDM4EKMT2APOLB
SCHEMBL2044625 0.92 MAPT (0.55) MAPTALDH1A1KDM4EKMT2APOLB
SCHEMBL2044628 0.92 MAPT (0.55) MAPTALDH1A1KDM4EKMT2APOLB
SCHEMBL214717 0.91 MAPT (0.49) MAPTALDH1A1KDM4EKMT2APOLB
SCHEMBL214718 0.91 MAPT (0.49) MAPTALDH1A1KDM4EKMT2APOLB
SCHEMBL212578 0.89 MAPT (0.48) MAPTALDH1A1KDM4EKMT2APOLB
SCHEMBL212579 0.89 MAPT (0.48) MAPTALDH1A1KDM4EKMT2APOLB
SCHEMBL211991 0.88 MAPT (0.47) MAPTALDH1A1KDM4EKMT2AMEN1
SCHEMBL213246 0.88 MAPT (0.47) MAPTALDH1A1KDM4EKMT2AMEN1
SCHEMBL213245 0.88 MAPT (0.47) MAPTALDH1A1KDM4EKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120077941-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2012-03-29 US claimed
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US claimed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US claimed
US-8541509-B2 Polymers functionalized with protected oxime compounds BRIDGESTONE CORPORATION (JP) 2013-09-24 US disclosed
US-20120077941-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2012-03-29 US disclosed
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US disclosed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US disclosed