Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2122669 | 0.91 | S1PR1 (0.49) | S1PR1S1PR3 | |
| SCHEMBL2122212 | 0.88 | S1PR1 (0.47) | S1PR1S1PR3 | |
| SCHEMBL2122146 | 0.86 | S1PR1 (0.50) | S1PR1S1PR3 | |
| SCHEMBL3664926 | 0.84 | S1PR1 (0.60) | S1PR1S1PR3 | |
| SCHEMBL2122672 | 0.79 | S1PR1 (0.49) | S1PR1S1PR3 | |
| SCHEMBL2116707 | 0.78 | S1PR1 (0.52) | S1PR1S1PR3 | |
| SCHEMBL3664827 | 0.76 | S1PR1 (0.47) | S1PR1S1PR3 | |
| SCHEMBL2122214 | 0.74 | S1PR1 (0.50) | S1PR1S1PR3 | |
| SCHEMBL2124787 | 0.74 | S1PR1 (0.49) | S1PR1S1PR3 | |
| SCHEMBL3664816 | 0.74 | S1PR1 (0.62) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443112-A1 | THIAZOLE OR THIADIZALOE DERIVATIVES FOR USE AS SPHINGOSINE 1-PHOSPHATE 1 (S1P1) RECEPTOR AGONISTS | Glaxo Group Limited (GB) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010145202-A1 | THIAZOLE OR THIADIZALOE DERIVATIVES FOR USE AS SPHINGOSINE 1-PHOSPHATE 1 (S1P1) RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2010-12-23 | — | — | WO | disclosed |