Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214217 | 0.82 | HDAC1 (0.33) | METHDAC1HDAC2GSK3B | |
| SCHEMBL213505 | 0.76 | GAA (0.40) | METHDAC1HDAC2GSK3B | |
| SCHEMBL213506 | 0.76 | GAA (0.40) | METHDAC1HDAC2GSK3B | |
| SCHEMBL213653 | 0.73 | HDAC1 (0.34) | METHDAC1HDAC2GSK3B | |
| SCHEMBL213652 | 0.73 | HDAC1 (0.34) | METHDAC1HDAC2GSK3B | |
| SCHEMBL212496 | 0.73 | — | — | |
| SCHEMBL1253531 | 0.72 | NPC1 (0.39) | METHDAC1HDAC2GSK3B | |
| SCHEMBL214475 | 0.70 | MAPT (0.43) | HDAC1HDAC2GSK3B | |
| SCHEMBL214476 | 0.70 | MAPT (0.43) | HDAC1HDAC2GSK3B | |
| SCHEMBL1577120 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088868-B2 | oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis | BRIDGESTONE CORPORATION (JP) | 2012-01-03 | — | — | US | claimed |
| US-20080146745-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2008-06-19 | — | — | US | claimed |
| US-8088868-B2 | oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis | BRIDGESTONE CORPORATION (JP) | 2012-01-03 | — | — | US | disclosed |
| US-20080146745-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2008-06-19 | — | — | US | disclosed |