Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 20/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21223701 | 0.93 | HDAC4 (0.70) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL14645583 | 0.84 | HDAC4 (1.00) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL21223349 | 0.83 | HDAC4 (0.71) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL21223467 | 0.83 | HDAC4 (0.70) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL14645607 | 0.82 | HDAC4 (1.00) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL21223842 | 0.82 | HDAC4 (0.64) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL21223530 | 0.82 | HDAC4 (0.64) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL21223599 | 0.81 | HDAC4 (0.70) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL20838051 | 0.81 | HDAC4 (0.78) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL19030803 | 0.80 | HDAC4 (0.76) | HDAC4HDAC6HDAC8HDAC2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11286242-B2 | Oxadiazoles for use in controlling phytopathogenic fungi | PI INDUSTRIES LTD. (IN) | 2022-03-29 | — | — | US | claimed |
| CN-112004813-A | Oxadiazole compounds for controlling phytopathogenic fungi | PI工业有限公司 | 2020-11-27 | — | — | CN | claimed |
| US-20200354326-A1 | OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2020-11-12 | — | — | US | claimed |
| WO-2019150219-A9 | OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2019-11-28 | — | — | WO | claimed |
| US-20220169621-A1 | OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-06-02 | — | — | US | disclosed |
| US-11286242-B2 | Oxadiazoles for use in controlling phytopathogenic fungi | PI INDUSTRIES LTD. (IN) | 2022-03-29 | — | — | US | disclosed |
| EP-3746439-A2 | OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI | PI Industries Ltd. (IN) | 2020-12-09 | — | — | EP | disclosed |
| CN-112004813-A | Oxadiazole compounds for controlling phytopathogenic fungi | PI工业有限公司 | 2020-11-27 | — | — | CN | disclosed |
| US-20200354326-A1 | OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2020-11-12 | — | — | US | disclosed |
| WO-2019150219-A9 | OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2019-11-28 | — | — | WO | disclosed |
| WO-2019150219-A2 | NOVEL OXADIAZOLES | PI INDUSTRIES LTD. (IN) | 2019-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11286242-B2 | Oxadiazoles for use in controlling phytopathogenic fungi | OXA1L, CYP51A1, CYP1A1 | HDAC4 2246/4885HDAC6 1374/4885HDAC8 2756/4885 |
| US-20200354326-A1 | OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI | OXA1L, CYP51A1, CYP1A1 | HDAC4 2246/4885HDAC6 1374/4885HDAC8 2756/4885 |
| US-20220169621-A1 | OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI | OXA1L, CYP51A1, CYP1A1 | HDAC4 2246/4885HDAC6 1374/4885HDAC8 2756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.