Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 10/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.78 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.74 |
| ▸ | PGR | P06401 | 2/20 | 0.74 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | SHBG | P04278 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | AR | P10275 | 1/20 | 0.74 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1685788 | 0.92 | HIF1A (0.81) | HIF1ALMNANR3C1SMN1; SMN2NR3C2 | |
| SCHEMBL12045184 | 0.92 | HIF1A (0.81) | HIF1ALMNANR3C1SMN1; SMN2NR3C2 | |
| SCHEMBL13044945 | 0.92 | HIF1A (0.81) | HIF1ALMNANR3C1SMN1; SMN2NR3C2 | |
| SCHEMBL22872809 | 0.92 | HIF1A (0.81) | HIF1ALMNANR3C1SMN1; SMN2NR3C2 | |
| SCHEMBL1685787 | 0.92 | HIF1A (0.81) | HIF1ALMNANR3C1SMN1; SMN2NR3C2 | |
| SCHEMBL21340506 | 0.89 | HIF1A (0.75) | HIF1ALMNANR3C1SMN1; SMN2NR3C2 | |
| SCHEMBL1685722 | 0.89 | HIF1A (0.77) | HIF1ALMNANR3C1SMN1; SMN2NR3C2 | |
| SCHEMBL25854534 | 0.89 | HIF1A (0.77) | HIF1ALMNANR3C1SMN1; SMN2NR3C2 | |
| SCHEMBL1685723 | 0.89 | HIF1A (0.77) | HIF1ALMNANR3C1SMN1; SMN2NR3C2 | |
| SCHEMBL14523057 | 0.88 | HIF1A (1.00) | HIF1ALMNANR3C1SMN1; SMN2NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019148293-A1 | GLASS FORMULATIONS COMPRISING STEROID DIMERS AND USES THEREOF | INTERFACE BIOLOGICS, INC. (CA) | 2019-08-08 | — | — | WO | disclosed |