Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 18/20 | 0.45 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21231595 | 0.83 | FASN (0.64) | FASN | |
| SCHEMBL22536686 | 0.81 | FASN (0.45) | FASNHRH3 | |
| SCHEMBL21231377 | 0.81 | FASN (0.61) | FASN | |
| SCHEMBL21231550 | 0.80 | FASN (0.52) | FASNGHSR | |
| SCHEMBL21231558 | 0.78 | FASN (0.48) | FASNGHSR | |
| SCHEMBL21231784 | 0.78 | FASN (0.53) | FASN | |
| SCHEMBL21231475 | 0.78 | FASN (0.49) | FASNHRH3 | |
| SCHEMBL22536662 | 0.78 | FASN (0.63) | FASN | |
| SCHEMBL21234236 | 0.75 | CCNK (0.50) | FASNHRH3 | |
| SCHEMBL19542415 | 0.75 | FASN (0.70) | FASNHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190241533-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR INHIBITION OF FASN | FORMA THERAPEUTICS, INC. | 2019-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190241533-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR INHIBITION OF FASN | FASN, FABP1, SCD | FASN 1/4885GHSR 4652/4885HRH3 4167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.