Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 20/20 | 0.82 |
| ▸ | CTSK | P43235 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21233250 | 0.90 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL18373159 | 0.90 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL21173001 | 0.88 | CTSC (0.81) | CTSCCTSK | |
| SCHEMBL21233268 | 0.84 | CTSC (0.83) | CTSCCTSK | |
| SCHEMBL18373160 | 0.83 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL21441006 | 0.83 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL21172969 | 0.81 | CTSC (0.85) | CTSCCTSK | |
| SCHEMBL21233136 | 0.80 | CTSC (0.87) | CTSCCTSK | |
| SCHEMBL17584767 | 0.79 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL18373221 | 0.78 | CTSC (1.00) | CTSCCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191487-B1 | SPIROCYCLIC INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INT (DE) | 2019-08-07 | — | — | EP | disclosed |