Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | CCNC | P24863 | 2/20 | 0.31 |
| ▸ | CDK8 | P49336 | 2/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241221 | 0.81 | BRD4 (0.36) | PDE1APDE1BPDE1CBRD4HPGDS | |
| SCHEMBL21597748 | 0.78 | BRD4 (0.36) | PDE1APDE1BPDE1CBRD4HPGD | |
| SCHEMBL26638827 | 0.75 | KDM4E (0.44) | BRD4ADORA2A | |
| SCHEMBL26785868 | 0.75 | ADORA2A (0.35) | PDE1APDE1BPDE1CBRD4ADORA2A | |
| SCHEMBL22952445 | 0.74 | BRD4 (0.33) | BRD4CCNCCDK8PDE10A | |
| SCHEMBL21604025 | 0.74 | BRD4 (0.33) | PDE1APDE1BPDE1CBRD4ADORA2A | |
| SCHEMBL25722867 | 0.71 | PTGS1 (0.50) | HPGDADORA2APDE10A | |
| SCHEMBL31412366 | 0.71 | BRD4 (0.36) | BRD4ADORA2ACCNCCDK8HCRTR1 | |
| SCHEMBL30641566 | 0.70 | JMJD6 (0.42) | BRD4HPGDSLTA4HCCNCCDK8 | |
| SCHEMBL30641565 | 0.70 | JMJD6 (0.42) | BRD4HPGDSLTA4HCCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019148851-A1 | FIVE-MEMBERED RING-SUBSTITUTED PYRIDAZINOL COMPOUND AND DERIVATIVES THEREOF, PREPARATION METHOD, HERBICIDAL COMPOSITION, AND APPLICATION | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |