Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16327450 | 1.00 | GLP1R (0.45) | GLP1RTSHRFOLH1KDM4ELMNA | |
| SCHEMBL25355950 | 0.92 | TSHR (0.50) | GLP1RTSHRFOLH1KDM4ELMNA | |
| SCHEMBL25355952 | 0.92 | TSHR (0.50) | GLP1RTSHRFOLH1KDM4ELMNA | |
| SCHEMBL22872352 | 0.91 | GLP1R (0.46) | GLP1RTSHRFOLH1KDM4ELMNA | |
| SCHEMBL12171769 | 0.90 | GLP1R (0.55) | GLP1RTSHRFOLH1ALBDGAT1 | |
| SCHEMBL30757553 | 0.90 | GLP1R (0.55) | GLP1RTSHRFOLH1ALBDGAT1 | |
| SCHEMBL13963172 | 0.88 | GLP1R (0.44) | GLP1RTSHRFOLH1KDM4ELMNA | |
| SCHEMBL16639044 | 0.88 | GLP1R (0.44) | GLP1RTSHRFOLH1KDM4ELMNA | |
| SCHEMBL25128698 | 0.87 | TSHR (0.43) | GLP1RTSHRFOLH1KDM4ELMNA | |
| SCHEMBL25128745 | 0.87 | TSHR (0.43) | GLP1RTSHRFOLH1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149637-A1 | ANTIBODY DRUG CONJUGATES (ADCS) WITH NAMPT INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2019-08-08 | — | — | WO | disclosed |