Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 6/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | ADCY10 | Q96PN6 | 3/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TPH1 | P17752 | 2/20 | 0.32 |
| ▸ | TPH2 | Q8IWU9 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18756168 | 0.83 | CHRM1 (0.45) | CHRM1KEAP1KMT2ACYP19A1ADCY10 | |
| SCHEMBL18756173 | 0.82 | CHRM1 (0.39) | CHRM1KEAP1KMT2ACYP19A1ADCY10 | |
| SCHEMBL18725526 | 0.80 | CHRM1 (0.45) | CHRM1KMT2AADCY10MEN1MAPT | |
| SCHEMBL18756044 | 0.79 | CHRM1 (0.39) | CHRM1KEAP1KMT2ACYP19A1SCN4A | |
| SCHEMBL21235440 | 0.75 | CHRM1 (0.48) | CHRM1P2RX7 | |
| SCHEMBL18725436 | 0.75 | CHRM1 (0.72) | CHRM1 | |
| SCHEMBL21235424 | 0.74 | CHRM1 (0.49) | CHRM1 | |
| SCHEMBL18756167 | 0.74 | CHRM1 (0.49) | CHRM1 | |
| SCHEMBL18725358 | 0.74 | CHRM1 (0.73) | CHRM1 | |
| SCHEMBL21235235 | 0.74 | KDM4E (0.46) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156397-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2019-08-07 | — | — | EP | disclosed |