⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29204873 | 0.97 | — | — | |
| SCHEMBL13799019 | 0.78 | — | — | |
| SCHEMBL30759501 | 0.75 | — | — | |
| SCHEMBL2121756 | 0.72 | TP53 (0.33) | — | |
| SCHEMBL11004435 | 0.72 | — | — | |
| SCHEMBL19488165 | 0.71 | — | — | |
| SCHEMBL11518869 | 0.71 | — | — | |
| SCHEMBL11123194 | 0.71 | — | — | |
| SCHEMBL7830347 | 0.69 | — | — | |
| SCHEMBL31248142 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111040060-B | Method for polymerizing 'active' free radical of vinyl monomer under near-infrared photo-thermal conversion | 苏州大学 | 2020-12-29 | — | — | CN | claimed |
| CN-111040060-A | Method for polymerizing 'active' free radical of vinyl monomer under near-infrared photo-thermal conversion | 苏州大学 | 2020-04-21 | — | — | CN | claimed |
| CN-110128578-B | Light-controlled aqueous solution reversible complexing polymerization and preparation of polymer nanoparticles | 苏州大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-111040060-B | Method for polymerizing 'active' free radical of vinyl monomer under near-infrared photo-thermal conversion | 苏州大学 | 2020-12-29 | — | — | CN | disclosed |
| CN-111040060-A | Method for polymerizing 'active' free radical of vinyl monomer under near-infrared photo-thermal conversion | 苏州大学 | 2020-04-21 | — | — | CN | disclosed |
| WO-2020021735-A1 | RESIN-COATED METALLIC PIGMENT | DIC株式会社 | 2020-01-30 | — | — | WO | disclosed |
| US-9814709-B2 | Bruton's tyrosine kinase inhibitor | HEFEI INSTITUTES OF PHYSICAL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) | 2017-11-14 | — | — | US | disclosed |
| US-20170128439-A1 | NEW BRUTON'S TYROSINE KINASE INHIBITOR | ANHUI NEW STAR PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) | 2017-05-11 | — | — | US | disclosed |
| US-8865863-B2 | MCR dendrimers | Leibniz-Institut fur Pflandzenbiochemie (DE) | 2014-10-21 | — | — | US | disclosed |
| US-20130203960-A1 | MCR DENDRIMERS | Leibniz-Institut fur Pflanzenbiochemie (DE) | 2013-08-08 | — | — | US | disclosed |
| US-20120095011-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2012-04-19 | — | — | US | disclosed |
| US-20090131463-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2009-05-21 | — | — | US | disclosed |
| US-7521453-B2 | e.g. 5-Bromo-2-(3-methylisoxazol-5-ylmethylamino)-4-(5-cyclopropyl- 1H-pyrazol-3-ylamino)pyrimidine; anticarcinogenic, antitumor agents; breast, prostate, colon cancer | ASTRAZENECA AB (SE) | 2009-04-21 | — | — | US | disclosed |
| EP-1456182-B1 | PYRIMIDINE DERIVATIVES AS MODULATORS OF INSULINE-LIKE GROWTH FACTOR-1 RECEPTOR (IGF-I) | ASTRAZENECA AB (SE) | 2009-03-11 | — | — | EP | disclosed |
| CN-1289486-C | Pyrimidine derivatives as modulators of insulin-like growth factor-1 receptor (igf-1) | ASTRAZENECA AB (SE) | 2006-12-13 | — | — | CN | disclosed |
| CN-1617858-A | Pyrimidine derivatives as modulators of insulin-like growth factor-1 receptor (igf-1) | ASTRAZENECA AB (SE) | 2005-05-18 | — | — | CN | disclosed |
| US-20050054638-A1 | Pyrimidine derivatives as modulators of insulin-like growth factor-1 receptor (igf-i) | ASTRAZENECA AB | 2005-03-10 | — | — | US | disclosed |
| US-4339591-A | Process for the production of caboxylic acid cyanides | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1982-07-13 | — | — | US | disclosed |
| US-4161491-A | Process for the production of alpha-ketocarboxylic acid amides and cycloaliphatic products | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1979-07-17 | — | — | US | disclosed |