Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29099091 | 0.86 | IDO1 (0.53) | IDO1ALDH1A1HPGDALOX15NPSR1 | |
| SCHEMBL30628110 | 0.86 | IDO1 (0.53) | IDO1ALDH1A1HPGDALOX15NPSR1 | |
| SCHEMBL123581 | 0.86 | IDO1 (0.54) | IDO1ALDH1A1HPGDALOX15NPSR1 | |
| SCHEMBL29376679 | 0.86 | IDO1 (0.54) | IDO1ALDH1A1HPGDALOX15NPSR1 | |
| SCHEMBL30628100 | 0.85 | IDO1 (0.50) | IDO1 | |
| SCHEMBL29099096 | 0.85 | IDO1 (0.50) | IDO1 | |
| SCHEMBL30628067 | 0.85 | IDO1 (0.51) | IDO1 | |
| SCHEMBL29099152 | 0.85 | IDO1 (0.51) | IDO1 | |
| SCHEMBL21236453 | 0.84 | IDO1 (0.51) | IDO1 | |
| SCHEMBL30100166 | 0.84 | IDO1 (0.51) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149255-A1 | INDOLEAMINE-2,3-DIOXYGENASE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 成都海创药业有限公司 | 2019-08-08 | — | — | WO | disclosed |