Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 7/20 | 0.55 |
| ▸ | KDM1B | Q8NB78 | 3/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | HTR2C | P28335 | 8/20 | 0.45 |
| ▸ | HTR2B | P41595 | 8/20 | 0.45 |
| ▸ | HTR2A | P28223 | 6/20 | 0.45 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21236291 | 0.80 | KDM1A (0.60) | KDM1AKDM1BKCNH2HTR2CHTR2B | |
| SCHEMBL22334917 | 0.80 | KDM1A (0.60) | KDM1AKDM1BKCNH2HTR2CHTR2B | |
| SCHEMBL15270956 | 0.77 | HTR2C (0.59) | KDM1AKDM1BKCNH2HTR2CHTR2B | |
| SCHEMBL21236196 | 0.76 | KDM1A (0.60) | KDM1AKDM1BKCNH2HTR2CHTR2B | |
| SCHEMBL21236194 | 0.76 | KDM1A (0.60) | KDM1AKDM1BKCNH2HTR2CHTR2B | |
| SCHEMBL26376200 | 0.72 | KDM1A (1.00) | KDM1AKDM1BKCNH2RCOR1 | |
| SCHEMBL21236290 | 0.72 | KDM1A (0.68) | KDM1AKDM1BKCNH2HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL25377867 | 0.70 | KDM1A (0.96) | KDM1AKDM1BKCNH2RCOR1 | |
| Hydrochloric Acid SCHEMBL25377871 | 0.70 | KDM1A (0.96) | KDM1AKDM1BKCNH2RCOR1 | |
| SCHEMBL21236193 | 0.70 | KDM1A (0.60) | KDM1AKDM1BKCNH2HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149734-A1 | CYCLOALKYL SUBSTITUTED PYRAZOLOPYRIMIDINES HAVING ACTIVITY AGAINST RSV | Janssen Sciences Ireland Unlimited Company (IE) | 2019-08-08 | — | — | WO | disclosed |