Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.69 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.59 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2124330 | 0.89 | S1PR1 (0.68) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2121688 | 0.88 | S1PR1 (0.73) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2124009 | 0.87 | S1PR1 (0.66) | S1PR1S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL2123009 | 0.87 | S1PR1 (0.72) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2123471 | 0.86 | S1PR1 (0.71) | S1PR1S1PR3S1PR5 | |
| SCHEMBL3428386 | 0.86 | S1PR1 (0.73) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2605783 | 0.85 | S1PR1 (0.64) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2605659 | 0.85 | S1PR1 (0.64) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2132942 | 0.85 | S1PR1 (0.68) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2128972 | 0.85 | S1PR1 (0.68) | S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443110-A1 | S1P1 AGONISTS COMPRISING A BICYCLIC N-CONTAINING RING | Glaxo Group Limited (GB) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010146105-A1 | S1P1 AGONISTS COMPRISING A BICYCLIC N-CONTAINING RING | GLAXO GROUP LIMITED (GB) | 2010-12-23 | — | — | WO | disclosed |