Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 18/20 | 0.62 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21236940 | 0.83 | SCN9A (0.71) | SCN9A | |
| SCHEMBL805976 | 0.82 | SCN9A (0.56) | SCN9A | |
| SCHEMBL21236904 | 0.80 | SCN9A (0.69) | SCN9A | |
| SCHEMBL21236834 | 0.79 | SCN9A (0.62) | SCN9A | |
| SCHEMBL29421398 | 0.77 | SCN9A (1.00) | SCN9A | |
| SCHEMBL29421403 | 0.77 | SCN9A (1.00) | SCN9A | |
| SCHEMBL786988 | 0.77 | SCN9A (1.00) | SCN9A | |
| SCHEMBL29421396 | 0.77 | SCN9A (1.00) | SCN9A | |
| SCHEMBL792513 | 0.77 | SCN9A (1.00) | SCN9A | |
| SCHEMBL787483 | 0.77 | SCN9A (1.00) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616441-B1 | PYRIDINE COMPOUNDS AND THE USES THEREOF | PURDUE PHARMA LP (US) | 2019-08-07 | — | — | EP | disclosed |