Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 19/20 | 0.67 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
| ▸ | FPR2 | P25090 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805896 | 0.81 | SCN9A (0.66) | SCN9ACHEK2FPR2 | |
| SCHEMBL21236966 | 0.81 | SCN9A (0.53) | SCN9AFPR2 | |
| SCHEMBL21236950 | 0.81 | SCN9A (0.65) | SCN9AFPR2 | |
| SCHEMBL793657 | 0.80 | SCN9A (1.00) | SCN9A | |
| SCHEMBL787611 | 0.80 | SCN9A (1.00) | SCN9A | |
| SCHEMBL787612 | 0.80 | SCN9A (1.00) | SCN9A | |
| SCHEMBL21236837 | 0.80 | SCN9A (0.72) | SCN9A | |
| SCHEMBL805976 | 0.77 | SCN9A (0.56) | SCN9A | |
| SCHEMBL21236974 | 0.76 | SCN9A (0.69) | SCN9A | |
| SCHEMBL1758373 | 0.76 | SCN9A (0.57) | SCN9ACHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616441-B1 | PYRIDINE COMPOUNDS AND THE USES THEREOF | PURDUE PHARMA LP (US) | 2019-08-07 | — | — | EP | disclosed |