Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 14/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805915 | 0.90 | SCN9A (0.67) | SCN9AKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL15383836 | 0.85 | SCN9A (0.60) | SCN9AKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL21236837 | 0.78 | SCN9A (0.72) | SCN9A | |
| SCHEMBL787725 | 0.78 | SCN9A (1.00) | SCN9A | |
| SCHEMBL21236906 | 0.78 | SCN9A (0.65) | SCN9A | |
| SCHEMBL787549 | 0.78 | SCN9A (1.00) | SCN9A | |
| SCHEMBL787548 | 0.78 | SCN9A (1.00) | SCN9A | |
| SCHEMBL805982 | 0.78 | SCN9A (0.64) | SCN9AKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL806028 | 0.77 | SCN9A (0.68) | SCN9AKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL805985 | 0.74 | SCN9A (0.60) | SCN9AKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616441-B1 | PYRIDINE COMPOUNDS AND THE USES THEREOF | PURDUE PHARMA LP (US) | 2019-08-07 | — | — | EP | disclosed |