Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 19/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29421488 | 0.85 | SCN9A (1.00) | SCN9A | |
| SCHEMBL787530 | 0.85 | SCN9A (1.00) | SCN9A | |
| SCHEMBL787067 | 0.84 | SCN9A (1.00) | SCN9A | |
| SCHEMBL21236984 | 0.80 | SCN9A (0.78) | SCN9A | |
| SCHEMBL21236929 | 0.79 | SCN9A (0.71) | SCN9A | |
| SCHEMBL787329 | 0.73 | SCN9A (1.00) | SCN9A | |
| SCHEMBL787438 | 0.72 | SCN9A (1.00) | SCN9A | |
| SCHEMBL10284480 | 0.71 | SCN9A (0.78) | SCN9A | |
| SCHEMBL805902 | 0.71 | SCN9A (0.80) | SCN9A | |
| SCHEMBL21236849 | 0.70 | SCN9A (0.61) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616441-B1 | PYRIDINE COMPOUNDS AND THE USES THEREOF | PURDUE PHARMA LP (US) | 2019-08-07 | — | — | EP | disclosed |