Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21238938 | 0.82 | CYP11B1 (0.42) | — | |
| SCHEMBL17456001 | 0.81 | PIK3CD (0.46) | PDE10APIK3CDPIK3CA | |
| SCHEMBL17455962 | 0.79 | PDE10A (0.45) | PDE10APIK3CDPIK3CA | |
| SCHEMBL17456051 | 0.77 | PIK3CD (0.54) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19575426 | 0.77 | LRRK2 (0.47) | LRRK2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL18502888 | 0.77 | PDE3B (0.50) | PDE10A | |
| SCHEMBL1935804 | 0.77 | PDE3B (0.50) | PDE10A | |
| SCHEMBL23609421 | 0.77 | SSTR4 (0.50) | LRRK2 | |
| SCHEMBL17456027 | 0.77 | CHRM1 (0.46) | PDE10APIK3CDPIK3CA | |
| SCHEMBL17456042 | 0.76 | SCN9A (0.52) | PDE10ALRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982666-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2019-08-07 | — | — | EP | disclosed |