Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MRGPRX1 | Q96LB2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18332106 | 0.74 | MEN1 (0.53) | MEN1KMT2ALMNAHTTMRGPRX1 | |
| SCHEMBL18331405 | 0.74 | MEN1 (0.60) | MEN1KMT2ALMNAHTTMRGPRX1 | |
| SCHEMBL8460938 | 0.71 | KMT2A (0.66) | MEN1KMT2ALMNAHTTMRGPRX1 | |
| SCHEMBL18330595 | 0.70 | MEN1 (0.52) | MEN1KMT2ALMNAHTTMRGPRX1 | |
| SCHEMBL20085268 | 0.70 | MEN1 (0.46) | MEN1KMT2ALMNAHTTMRGPRX1 | |
| SCHEMBL20084858 | 0.70 | MEN1 (0.46) | MEN1KMT2ALMNAHTTMRGPRX1 | |
| SCHEMBL20084564 | 0.70 | MEN1 (0.49) | MEN1KMT2ALMNAHTTMRGPRX1 | |
| SCHEMBL16168677 | 0.70 | PTGS1 (0.45) | MEN1KMT2ANR1H3LMNAALDH1A1 | |
| SCHEMBL21572612 | 0.69 | MEN1 (0.51) | MEN1KMT2ALMNAHTTMRGPRX1 | |
| SCHEMBL20085248 | 0.69 | MEN1 (0.48) | MEN1KMT2ALMNAHTTMRGPRX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |