Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 10/20 | 0.52 |
| ▸ | GSK3B | P49841 | 7/20 | 0.52 |
| ▸ | WNT1 | P04628 | 2/20 | 0.52 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | LDLR | P01130 | 1/20 | 0.45 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19736130 | 0.74 | GSK3B (0.45) | IDO1DYRK1AGSK3BWNT1HPGDS | |
| SCHEMBL22874232 | 0.74 | IDO1 (0.59) | IDO1DYRK1AGSK3BWNT1HPGDS | |
| SCHEMBL17308284 | 0.74 | IDO1 (0.68) | IDO1DYRK1AGSK3BHPGDSLDLR | |
| SCHEMBL2837461 | 0.73 | IDO1 (0.62) | IDO1DYRK1AGSK3BWNT1HPGDS | |
| SCHEMBL19706556 | 0.73 | PIK3C3 (0.53) | DYRK1AGSK3BWNT1 | |
| Ammonia Solution, Strong SCHEMBL23407639 | 0.72 | USP2 (0.41) | DYRK1AGSK3BWNT1HTTCLK1 | |
| SCHEMBL1896511 | 0.72 | DYRK1A (0.65) | DYRK1AGSK3BNFATC1CLK1UHRF1 | |
| SCHEMBL30308690 | 0.72 | DYRK1A (0.65) | DYRK1AGSK3BNFATC1CLK1UHRF1 | |
| SCHEMBL1502339 | 0.72 | IDO1 (0.51) | IDO1DYRK1AGSK3BWNT1HPGDS | |
| SCHEMBL8019439 | 0.72 | LDLR (0.40) | IDO1DYRK1AGSK3BWNT1HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |