⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276337 | 0.80 | — | — | |
| SCHEMBL277140 | 0.77 | — | — | |
| SCHEMBL271082 | 0.76 | — | — | |
| SCHEMBL269518 | 0.76 | — | — | |
| SCHEMBL270131 | 0.62 | USP2 (0.36) | — | |
| SCHEMBL20609966 | 0.61 | TSHR (0.32) | — | |
| SCHEMBL23935906 | 0.60 | — | — | |
| SCHEMBL26806371 | 0.59 | — | — | |
| SCHEMBL270864 | 0.59 | — | — | |
| SCHEMBL25663949 | 0.59 | PIK3CD (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019152527-A1 | PIPECOLIC ESTERS FOR INHIBITION OF THE PROTEASOME | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-08-08 | — | — | WO | disclosed |